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Experience with pineal region tumors

J K Kang1, S S Jeun, Y K Hong

  • 1Department of Neurosurgery, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|April 21, 1998
PubMed
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This study on 43 pineal region tumors found varied outcomes based on tumor type. Tissue diagnosis is crucial for effective treatment and improved survival rates for these rare brain tumors.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pediatric oncology

Background:

  • Pineal region tumors are rare and diverse.
  • Treatment historically relied on markers and radiation response.
  • Surgical techniques have advanced, reducing risks.

Purpose of the Study:

  • To review the presentation and outcomes of pineal region tumors.
  • To evaluate treatment modalities and survival rates.
  • To emphasize the importance of tissue diagnosis.

Main Methods:

  • Retrospective review of 43 pineal region tumors (1982-1996).
  • Analysis of tumor types, locations, and treatment approaches (surgery, radiation, chemotherapy).
  • Evaluation of survival rates and mortality.

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Main Results:

  • Overall survival rate was 79.1% (34/43).
  • Germinomas treated with radiotherapy had an 87% 5-year survival.
  • Non-germinomatous tumors had a 33.3% mortality rate despite multimodal treatment.

Conclusions:

  • Pineal region tumor treatment must be tailored to specific histology.
  • Tissue diagnosis is essential for optimal treatment planning.
  • Improved surgical techniques have lowered mortality and morbidity.