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Updated: Aug 11, 2026

Crystallization of Membrane Proteins in Lipidic Mesophases
Published on: March 28, 2011
Crystallization and X-ray diffraction of crystals formed in water-plasticized amorphous lactose
K Jouppila1, J Kansikas, Y H Roos
1Department of Food Technology, P.O. Box 27 (Latokartanonkaari 7), University of Helsinki, Finland.
Abstract:
Effects of storage time and relative humidity on crystallization and crystal forms produced from amorphous lactose were investigated. Crystallization was observed from time-dependent loss of sorbed water and increasing intensities of peaks in X-ray diffraction patterns. The rate of crystallization increased with increasing storage relative humidity. Lactose crystallized mainly as alpha-lactose monohydrate and anhydrous crystals with alpha- and beta-lactose in a molar ratio of 5:3. The results suggested that the crystal form was defined by the early nucleation process. The crystallization data are important in modeling of crystallization phenomena and prediction of stability of lactose-containing food and pharmaceutical materials.
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