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Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Dammarane Triterpenes from the Leaves of Securinega melanthesoides
1Department of Pharmacy, Swiss Federal Institute of Technology (ETH) Zurich, CH-8057 Zürich, Switzerland, and Department of Chemistry, University of Papua New Guinea, Port Moresby, Papua New Guinea.
Abstract:
Two new dammarane triterpenoids, trans-securinegin [(20S)-24-methylidenedammarane-3alpha-yl(2E)-3-(4-hydroxyphenyl)-2-propenate (1)] and cis-securinegin [(20S)-24-methylidenedammarane-3alpha-yl(2Z)-3-(4-hydroxyphenyl)-2-propenate (2)], were isolated from the leaves of Securinega melanthesoides, along with the known compound bergenin. The structures of 1 and 2 were elucidated using spectroscopic methods, mainly 2D NMR techniques.

