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Updated: Aug 12, 2026

A Calcium Bioluminescence Assay for Functional Analysis of Mosquito (Aedes aegypti) and Tick (Rhipicephalus microplus) G Protein-coupled Receptors
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A Novel Insect Antifeedant Nonprotein Amino Acid from Calotropis gigantea
1Division of Entomology, Indian Agricultural Research Institute, New Delhi 110 012, India, Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi 110 012, India, and Department of Chemistry, M. M. Post Graduate College, Modinagar 201 204, UP, India.
Abstract:
Giganticine (1), a novel nonprotein amino acid, has been isolated from a methanol extract of the root bark of Calotropis gigantea and its structure established by spectroscopic methods. It exhibited a significant antifeedant activity against nymphs of the desert locust Schistocerca gregaria.
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