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[Diagnosis in pediatric "allergic" patients]
G M Amato1, G Amato, R Barcellona
1Istituto di Pediatria, Università degli Studi, Palermo.
Minerva Pediatrica
|April 29, 1998
Summary
In vivo and in vitro allergy tests show satisfactory agreement for inhaled allergens. Allergy test results, including eosinophil counts and total IgE, significantly differ between positive and negative patients.
Area of Science:
- Clinical Immunology
- Pediatrics
- Allergology
Context:
- Allergic diseases require accurate diagnostic tools for effective management.
- In vivo (prick) and in vitro (MAST-CLA) allergometric tests are crucial for therapeutic decisions in allergic patients.
- This study evaluates the real-world diagnostic capacity of these tests in pediatric patients.
Purpose:
- To retrospectively evaluate the diagnostic capacity of prick and MAST-CLA tests in pediatric allergic patients.
- To compare the agreement between prick and MAST-CLA tests for various allergens.
- To analyze the relationship between eosinophil counts, total IgE levels, and allergy test results.
Summary:
- A retrospective study of 459 pediatric patients (6 months-16 years) with allergic disorders was conducted.
- Prick and MAST-CLA tests demonstrated satisfactory agreement for inhaled allergens.
- Significant differences in eosinophil counts and total IgE levels were observed between patients positive and negative for allergens.
Impact:
- Findings support the utility of both prick and MAST-CLA tests in diagnosing pediatric allergies.
- The study highlights age-related patterns in allergen prevalence.
- Positive pollen sensitization is associated with a higher frequency of food allergen sensitization, suggesting cross-reactivity implications.