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Updated: Jul 28, 2026
10:05
Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
[Drug delivery system in cardiovascular drugs]
F Miyake1, A Kamogawa, M Sakakibara
1Second Department of Internal Medicine, St. Marianna University School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|April 29, 1998
Summary
Cardiovascular drug delivery systems vary, offering rapid or sustained release via oral, sublingual, or transdermal routes. Advanced methods enable localized drug delivery during coronary interventions.
Area of Science:
- Pharmacology
- Cardiovascular Medicine
- Drug Delivery Systems
Context:
- Cardiovascular pharmacotherapy relies on diverse drug delivery systems.
- Commonly prescribed receptor inhibitors include beta-blockers and angiotensin II receptor inhibitors.
- Administration routes range from rapid sublingual sprays to slow-release oral tablets and transdermal patches.
Purpose:
- To review the spectrum of drug delivery systems for cardiovascular medications.
- To highlight how different formulations and administration routes influence drug pharmacodynamics.
- To discuss emerging localized delivery methods in interventional cardiology.
Summary:
- Drug delivery systems for cardiovascular drugs encompass various formulations (tablets, sprays, patches) and administration routes (oral, sublingual, transdermal).
- Specific drug types, like Nifedipine, are available in formulations for short, long, and very long-term effects.
- Innovations permit targeted drug administration directly to coronary arteries via stents or balloon catheters during interventional procedures.
Impact:
- Understanding these systems optimizes therapeutic outcomes in cardiovascular disease management.
- Tailoring drug delivery enhances patient compliance and treatment efficacy.
- Localised delivery systems represent a significant advancement in interventional cardiovascular therapy.
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