Reference values of gastric intramucosal pH in children
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F Reinoso-Barbero1, C Calvo, F Ruza
1Department of Pediatric Anesthesiology, La Paz Children's Hospital, Madrid, Spain.
Insights
Gastric intramucosal pH (pHi) reference values were determined in healthy children undergoing surgery. Mean pHi was 7.35, similar to adult values, indicating normal gastric mucosal perfusion.
Area of Science:
- Pediatric Gastroenterology
- Anesthesiology
- Critical Care Medicine
Background:
- Gastric intramucosal pH (pHi) is a marker of gastric mucosal perfusion.
- Reference values for pHi in pediatric patients are not well-established.
- Understanding normal pHi is crucial for assessing critically ill children.
Purpose of the Study:
- To establish reference values for gastric intramucosal pH (pHi) in pediatric patients.
- To compare pediatric pHi values with those of adults.
- To assess the correlation between pHi and other physiological parameters.
Main Methods:
- Gastric tonometry was performed on 17 healthy children (6 months to 12 years) undergoing minor surgery.
- A sigmoid tonometry catheter was inserted into the stomach.
- Gastric pHi was calculated using the Henderson-Hasselbalch equation with arterial blood gas analysis.
Main Results:
- The mean gastric pHi in healthy children was 7.35 ± 0.06.
- This value falls within the normal range for the general population (7.31-7.40).
- No significant correlation was found between pHi and arterial pH, bicarbonate, or base excess.
Conclusions:
- Healthy children under general anesthesia exhibit gastric intramucosal pH values comparable to adults.
- These findings provide valuable reference data for pediatric gastric tonometry.
- Gastric tonometry can be a reliable tool for assessing gastric mucosal perfusion in children.
Abstract:
To determine the reference values of gastric intramucosal pH (pHi) by tonometry in paediatric patients, we studied 17 children (nine males, eight females) with no systemic or gastrointestinal disease, aged six months to 12 years undergoing minor reconstructive surgery. Following anaesthetic induction a sigmoid tonometry catheter was inserted (Tonometrics, Inc.) into the stomach of the patients under direct vision. All children were normoventilated and were haemodynamically stable. After an equilibration period of 30 min, gastric pHi was calculated by applying the Henderson-Hasselbalch equation on the PCO2 obtained with the tonometer and the bicarbonate from the arterial blood gas analysis. The mean gastric pHi in our patients was 7.35 +/- 0.06 (SD). The normal pHi in the general population is estimated to be 7.31-7.40, with a confidence interval of 99%. No correlation was found between pHi and arterial pH, bicarbonate or base excess. Under conditions of normal ventilation and haemodynamic stability, healthy children during general anaesthesia have gastric intramucosal values similar to those of adults.
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