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Related Experiment Videos

Normal fetal thyroid volume

S S Ho1, C Metreweli

  • 1Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Hong Kong.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|April 29, 1998
PubMed
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This study established a fetal thyroid volume nomogram, finding fetal thyroid volume correlates with fetal weight and gestational age. Postnatal criteria may underestimate fetal thyroid size, necessitating gestational age consideration for evaluating fetal goiter.

Area of Science:

  • Fetal Medicine
  • Endocrinology
  • Medical Imaging

Background:

  • Normal fetal thyroid volume is crucial for assessing fetal well-being.
  • Existing criteria may underestimate fetal thyroid size compared to postnatal standards.

Purpose of the Study:

  • To establish a nomogram for normal fetal thyroid volume in relation to gestational age.
  • To investigate the correlation between fetal thyroid volume, estimated fetal weight, and gestational age.

Main Methods:

  • Prospective study of 289 normal fetuses (20-36 weeks gestation).
  • Fetal thyroid volume calculated using the ellipsoid equation.
  • Established a nomogram relating fetal thyroid volume to gestational age.

Main Results:

Related Experiment Videos

  • Mean fetal thyroid volume: 0.23 ± 0.18 cm³.
  • Fetal thyroid volume to estimated fetal weight ratio (V/W ratio) remained constant.
  • Fetal thyroid volume significantly correlated with estimated fetal weight (dominant factor) and gestational age.
  • Accelerated thyroid growth observed after 32 weeks gestation.

Conclusions:

  • The developed nomogram provides a reference for normal fetal thyroid volume.
  • Fetal thyroid enlargement may be underestimated using postnatal criteria.
  • Gestational age and the established nomogram are essential for evaluating potential fetal goiter.