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Effect of angiotensin infusion on plasma endothelin in pregnancy
F M Delemarre1, D de Jong, M A Didden
1Department of Obstetrics and Gynecology, Catharina Hospital Eindhoven, The Netherlands.
Objective:
To study a possible role of plasma endothelin in angiotensin-induced vasoconstriction.
Study Design:
Plasma endothelin levels were measured before and after an angiotensin sensitivity test at 32 gestational weeks in 19 nulliparous women.
Results:
No significant change in plasma endothelin occurred as a result of angiotensin infusion.
Conclusion:
The angiotensin-induced rise in diastolic blood pressure is not associated with changes in plasma endothelin.