Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Lung transplantation in children]

M O Hoekstra1, W van der Bij, W J de Boer

  • 1Afd. Kinderlongziekten, academisch Ziekenhuis, Groningen.

Nederlands Tijdschrift Voor Geneeskunde
|April 29, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Three Decades Single Center Experience of Airway Complications After Lung Transplantation.

Transplant international : official journal of the European Society for Organ Transplantation·2023
Same author

Diagnostic performance of FDG-PET/CT of post-transplant lymphoproliferative disorder and factors affecting diagnostic yield.

European journal of nuclear medicine and molecular imaging·2019
Same author

Patient-reported health outcomes in long-term lung transplantation survivors: A prospective cohort study.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
Same author

A Multicenter Study on Long-Term Outcomes After Lung Transplantation Comparing Donation After Circulatory Death and Donation After Brain Death.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
Same author

Effects of Supplementation of the Synbiotic Ecologic® 825/FOS P6 on Intestinal Barrier Function in Healthy Humans: A Randomized Controlled Trial.

PloS one·2016
Same author

Development of a Hyperactive Primary Hemostatic System During Off-Pump Lung Transplantation Resulting From an Unbalance Between von Willebrand Factor and Its Cleaving Protease ADAMTS13.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015

Lung transplantation offers a lifeline for chronic respiratory insufficiency, but faces challenges like donor shortages and rejection. Survival rates vary, emphasizing the need for careful patient selection and management.

Area of Science:

  • Medicine
  • Pulmonology
  • Transplant Surgery

Background:

  • Lung transplantation has been performed in the Netherlands since 1990 for chronic respiratory insufficiency.
  • Pediatric lung transplants are predominantly for cystic fibrosis, with significant pre-transplant attrition.
  • Donor lung scarcity leads to prolonged waiting times, exceeding one year.

Purpose of the Study:

  • To review the outcomes and challenges of lung transplantation in adults and children.
  • To highlight the complexities of pediatric lung transplantation, including patient selection and post-operative care.
  • To discuss survival rates and complications associated with lung transplantation.

Main Methods:

  • Retrospective analysis of lung transplantation cases in the Netherlands.

Related Experiment Videos

  • Review of patient referral, selection, and waiting list data.
  • Analysis of post-operative outcomes, including rejection rates, complications, and survival statistics.

    • Main Results:

    • Approximately one-third of referred pediatric patients undergo transplantation.
    • Acute rejection occurs in most patients, with chronic rejection in 20-40%.
    • One, two, and four-year survival rates range from 60-70%, 55-60%, and 30-50%, respectively.

    Conclusions:

    • Lung transplantation is a viable but complex treatment for chronic respiratory insufficiency.
    • Patient selection, management of rejection, and addressing donor shortages are critical for improving outcomes.
    • Timely referral and good pre-transplant condition are positive prognostic indicators.