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Abnormal spinal fluid in hypertensive encephalopathy

D Sehr1, W Hoffman, C Miles

  • 1Department of Neurosciences, USD School of Medicine; Sioux Falls, SD, USA.

South Dakota Journal of Medicine
|April 29, 1998
PubMed
Summary
This summary is machine-generated.

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Hypertensive encephalopathy typically involves mild inflammation, but this case showed significant white blood cell increase in spinal fluid. This unusual neutrophilic pleocytosis suggests a distinct pathological process in severe hypertension.

Area of Science:

  • Neurology
  • Nephrology
  • Internal Medicine

Background:

  • Hypertensive encephalopathy is a neurological emergency characterized by severe hypertension.
  • Cerebrospinal fluid (CSF) analysis is crucial for diagnosis, often revealing mild inflammatory changes.

Observation:

  • A 44-year-old male presented with severe hypertension and encephalopathy.
  • Cerebrospinal fluid analysis revealed a marked neutrophilic pleocytosis, indicating a significant white blood cell count.

Findings:

  • The presence of neutrophilic pleocytosis in hypertensive encephalopathy is highly unusual.
  • While lymphocytic pleocytosis is occasionally noted, a neutrophilic response is distinctly abnormal in this context.

Implications:

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  • This case highlights a potentially distinct pathophysiological mechanism in severe hypertensive encephalopathy.
  • Further research is needed to understand the significance and implications of neutrophilic pleocytosis in this condition.