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FT-IR spectroscopy as an emerging method for rapid characterization of microorganisms
G D Sockalingum1, W Bouhedja, P Pina
1Laboratoire de Spectroscopie Biomoléculaire, IFR 53, UFR de Pharmacie, Université de Reims Champagne-Ardenne, France.
Cellular and Molecular Biology (Noisy-Le-Grand, France)
|April 29, 1998
Abstract:
Statistical methods such as principal component analysis and cluster analysis were used to analyze ATR-FT-IR spectra obtained from bacterial whole cells. Both methods gave satisfactory results and are conclusive in showing that they can discriminate and classify bacterial strains of clinical origin exhibiting different resistance mechanisms. This approach places FT-IR spectroscopy at the forefront of those new potential techniques that could be used in the rapid screening of microorganisms.