Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bronchial responsiveness in active steelworkers

J L Corhay1, T Bury, R Louis

  • 1Dept of Pneumology, University of Liège, Belgium.

The European Respiratory Journal
|April 29, 1998
PubMed
Summary

Coke-oven workers exhibit significantly higher bronchial hyperresponsiveness (BHR), a risk factor for chronic bronchitis, compared to blast furnace workers. This suggests coke-oven pollutants are more potent irritants.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gemcitabine and low dose carboplatin in the treatment of elderly patients with advanced non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands)·2003
Same author

Structure of bacteriocin AS-48: from soluble state to membrane bound state.

Journal of molecular biology·2003
Same author

Crural artery bypass with the autogenous greater saphenous vein.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2003
Same author

[Predictive value of prenatal MRI in the diagnosis of thoracic congenital malformations].

Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica·2003
Same author

Weekly paclitaxel for advanced non-small cell lung cancer patients not suitable for platinum-based therapy.

Neoplasma·2003
Same author

Factors predictive of nephropathy in DCCT Type 1 diabetic patients with good or poor metabolic control.

Diabetic medicine : a journal of the British Diabetic Association·2003

Area of Science:

  • Occupational Health
  • Pulmonology
  • Environmental Medicine

Background:

  • Coke-oven workers face exposure to dust and irritant gases, increasing their risk of lung diseases like chronic bronchitis.
  • Nonspecific bronchial hyperresponsiveness (BHR) is a potential risk factor for chronic bronchitis development.
  • Previous studies indicated higher BHR prevalence in retired coke-oven workers.

Purpose of the Study:

  • To determine the prevalence and degree of BHR in active steelworkers, specifically comparing coke-oven workers and blast furnace workers.
  • To investigate the association between BHR and respiratory symptoms or lung function in these worker groups.

Main Methods:

  • A study involving 137 coke-oven workers and 150 blast furnace workers.
  • Methods included clinical examination, respiratory symptom questionnaires, pulmonary function testing, and methacholine aerosol challenge.

Related Experiment Videos

  • BHR was defined as a provocative concentration of methacholine causing a 20% fall in FEV1 (PC20) ≤ 8 mg/mL.

    • Main Results:

    • Coke-oven workers showed a significantly higher prevalence (31.4% vs. 6.7%) and degree of BHR compared to blast furnace workers (p<0.001).
    • Respiratory symptoms and basal bronchial obstruction were more frequent in coke-oven workers with BHR.
    • Basal maximum expiratory flow (25-75% FVC) and respiratory symptoms correlated with bronchial responsiveness.

    Conclusions:

    • Active coke-oven workers exhibit a higher prevalence and degree of BHR, suggesting coke-oven pollutants are more potent irritants than blast furnace emissions.
    • BHR may serve as a crucial indicator for chronic bronchitis risk in occupational settings.
    • Further research is needed to explore the impact of smoking and work duration on BHR in steelworkers.