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Related Experiment Videos

Celiac plexus block: a reappraisal

S Mercadante1, F Nicosia

  • 1Department of Anesthesia and Intensive Care, Buccheri La Ferla Hospital, Palermo, Italy.

Regional Anesthesia and Pain Medicine
|April 29, 1998
PubMed
Summary
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Neurolytic celiac plexus block offers effective pain relief for upper abdominal cancers, reducing opioid use in many patients. While generally safe, combination therapy is often needed for complete pain management.

Area of Science:

  • Pain Management
  • Interventional Radiology
  • Oncology

Background:

  • The neurolytic celiac plexus block is a key procedure for managing upper abdominal visceral pain in cancer patients.
  • Various techniques aim to improve efficacy and safety, but outcomes remain debated.

Purpose of the Study:

  • To review the literature on neurolytic celiac plexus block.
  • To assess its effectiveness, complications, and role in palliative care for abdominal malignancies.

Main Methods:

  • A literature survey of English language publications was conducted.
  • The review focused on anatomical, technical, and outcome-related aspects of the block.

Main Results:

  • Successful pain relief is achieved in 85% of pancreatic cancer patients and 73% of other abdominal malignancies.

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  • The block can reduce or eliminate the need for opioids, with an effect lasting over 4 weeks.
  • Serious complications are rare, but reporting deficiencies were noted across studies.

    • Conclusions:

    • Neurolytic celiac plexus block is a valuable adjuvant therapy for cancer pain, providing complete relief in some cases.
    • Combination palliative therapy is frequently necessary for optimal pain control.
    • Treatment failures can occur due to tumor spread or somatic pain components.