The effect of reinstatement stimulus conditions on the maintenance of long-term memory
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Updated: Oct 23, 2026

A Procedure for Studying the Footshock-Induced Reinstatement of Cocaine Seeking in Laboratory Rats
Published on: January 6, 2011
Abstract:
Weanling rats trained on an appetitive SDSdelta discrimination were subsequently exposed to different components of the training stimulus for 15 min each week for 10 successive weeks. On the week following the final stimulus exposure retention was measured by a 2-hr relearning test. Those subjects exposed to all acquisition cues (SDSdelta with reinforcement), as well as those exposed to Sdelta conditions alone, demonstrated enhanced retention relative to a control group receiving no reinstatement experience. All other exposure conditions including presentation of SD with reinforecement were either ineffective or impaired retention.
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