Why do children have chronic abdominal pain, and what happens to them when they grow up? Population based cohort

M Hotopf1, S Carr, R Mayou

  • 1Department of Psychological Medicine, King's College School of Medicine and Dentistry and Institute of Psychiatry, London SE5 8AZ, UK. m.hotopf@iop.bpmf.ac.uk

BMJ (Clinical Research Ed.)
|May 16, 1998
PubMed

Insights

Children with persistent abdominal pain often have parents with health issues. These children face a higher risk of adult psychiatric disorders, but not necessarily ongoing physical symptoms.

Area of Science:

  • Psychiatry
  • Developmental Pediatrics
  • Epidemiology

Background:

  • Persistent childhood abdominal pain is a common concern.
  • Parental health and family history may influence childhood conditions.
  • The long-term outcomes of childhood abdominal pain require further investigation.

Purpose of the Study:

  • To investigate the association between childhood abdominal pain and parental health.
  • To determine if childhood abdominal pain predicts adult medically unexplained symptoms and psychiatric disorders.

Main Methods:

  • Utilized a population-based birth cohort study design.
  • Included participants from the Medical Research Council (MRC) national survey of health and development.
  • Assessed childhood abdominal pain, parental health, and adult physical symptoms and psychiatric disorders at age 36.

Main Results:

  • Children with persistent abdominal pain had parents with higher rates of physical health complaints and maternal neuroticism.
  • These children showed a significantly increased likelihood of adult psychiatric disorders (OR 2.72).
  • No significant association was found for adult physical symptoms when psychiatric disorder was controlled (OR 1.39).

Conclusions:

  • Childhood persistent abdominal pain is linked to parental ill-health and emotional distress.
  • While not leading to persistent physical symptoms in adulthood, it increases the risk for psychiatric disorders.
  • This highlights the importance of considering family health and mental well-being in managing childhood abdominal pain.
Abstract

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...