Related Experiment Videos
[Current antimicrobial drugs]
M E van Kasteren1, S Natsch, J W van der Meer
1Academisch Ziekenhuis, afd. Algemene Interne Geneeskunde, Nijmegen.
Nederlands Tijdschrift Voor Geneeskunde
|April 29, 1998
Summary
Several new antibiotics offer improved treatment options for various infections, including intravenous and oral formulations. While new drug classes are emerging, innovative treatment strategies are still needed.
Area of Science:
- Pharmacology
- Infectious Diseases
Context:
- Recent years have seen the introduction of new antibiotics, expanding therapeutic options.
- However, significant advancements in novel treatment strategies for infections remain limited.
Purpose:
- To review newly available antibiotics and their potential applications.
- To highlight the progress in antimicrobial drug development.
Summary:
- New intravenous antibiotics include piperacillin-tazobactam, meropenem, cefepime, and cefpirome.
- Oral options feature third-generation cephalosporins (ceftibuten, cefetamet, cefpodoxime) and macrolides (clarithromycin, azithromycin), noted for improved dosing and tolerability over erythromycin.
- Promising new quinolones like trovafloxacin and treatments for Gram-positive infections such as teicoplanin and quinupristin-dalfopristin are also discussed.
Impact:
- The availability of these new antibiotics provides clinicians with expanded choices for managing bacterial infections.
- Further research into novel treatment strategies is crucial to combat evolving antimicrobial resistance.