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Radiation-induced cerebral meningiomas. Case reports

F Marconi1, G Parenti

  • 1Division of Neurosurgery, Hospital of Livorno, Italy.

Journal of Neurosurgical Sciences
|April 29, 1998
PubMed
Summary

Radiotherapy can cause meningiomas, tumors of the brain lining. This study reviews two cases, highlighting features of radiation-induced meningiomas and emphasizing cautious use of radiation therapy.

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Area of Science:

  • Neurology
  • Oncology
  • Radiology

Background:

  • External cranial irradiation is a known risk factor for secondary brain tumors.
  • Meningiomas are the most common type of secondary brain tumor following radiation exposure.

Purpose of the Study:

  • To present two cases of meningioma following external cranial irradiation.
  • To review features distinguishing radiation-induced meningiomas.
  • To emphasize the risks versus benefits of radiation therapy.

Main Methods:

  • Case study review.
  • Literature review of radiation-induced meningiomas.

Main Results:

  • Two patients developed meningiomas years after cranial irradiation for different conditions (Tinea capitis and astrocytoma).
  • Specific features suggest a causal link between radiotherapy and meningioma development.

Conclusions:

  • Radiation therapy can induce meningioma formation.
  • Careful consideration of risks and benefits is crucial when deciding on cranial irradiation.

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