Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cognitive function in patients with systemic sclerosis]

J Straszecka1, G Jonderko, E J Kucharz

  • 1IV Katedra i Klinika Chorób Wewnetrznych Sl. A.M., Tychy.

Polskie Archiwum Medycyny Wewnetrznej
|April 29, 1998
PubMed
Summary

Systemic sclerosis (SSc) patients often experience central nervous system issues, including memory and cognitive deficits, even with normal thyroid function. These neurological impairments suggest SSc affects the brain more frequently than previously recognized.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Significance of the angiotensin I/angiotensin II/angiotensin-(1-7) axis in the pathogenesis of systemic sclerosis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same author

Detecting and quantifying activity/inflammation in localized scleroderma with thermal imaging.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2018
Same author

Overweight and obesity may play a role in the pathogenesis of chronic spontaneous urticaria.

Clinical and experimental dermatology·2018
Same author

Serum androgens and prostate-specific antigen levels in androgenetic alopecia: is there a difference between frontal and vertex baldness?

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Body mass index and body surface area in scleroderma patients.

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Alopecia areata - hyperactivity of the hypothalamic-pituitary-adrenal axis is a myth?

Journal of the European Academy of Dermatology and Venereology : JEADV·2017

Area of Science:

  • Neurology
  • Rheumatology
  • Neuropsychology

Background:

  • Central nervous system (CNS) involvement is rarely documented in systemic sclerosis (SSc).
  • Cognitive function assessment is crucial for understanding the full impact of SSc on patients.

Purpose of the Study:

  • To investigate the prevalence and nature of cognitive dysfunction in patients with systemic sclerosis.
  • To differentiate CNS involvement related to SSc from effects of hypothyroidism.

Main Methods:

  • Cognitive functions were assessed in 21 systemic sclerosis patients and 42 healthy controls.
  • Thyroid function tests were performed to account for potential confounding effects.

Main Results:

  • Systemic sclerosis patients exhibited deficits in long-term memory, recent memory, learning, perception, and visuo-perceptual skills.

Related Experiment Videos

  • Prolonged simple reaction time was observed in SSc patients.
  • Cognitive impairments were present even in SSc patients with normal thyroid function, though less severe in those with hypothyroidism.

    • Conclusions:

    • Central nervous system involvement is more common in systemic sclerosis than previously reported.
    • Cognitive deficits are a significant feature of SSc, independent of thyroid status.
    • Further research into SSc-related neurological complications is warranted.