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Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
What you need to know: detecting alcohol problems in general medical practice
1Treatment Research Branch, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-7003, USA.
Primary care can improve early detection of alcohol abuse using validated screening tools like the Alcohol Use Disorders Identification Test (AUDIT). Combining self-reports with biochemical markers enhances accuracy in identifying problem drinkers.
Area of Science:
- General Practice
- Addiction Medicine
- Public Health
Background:
- Alcohol abuse and dependence affect a significant portion of patients in general medical clinics.
- Early detection of alcohol problems in primary care is crucial for timely intervention.
- Various screening strategies exist for identifying problem drinkers in clinical settings.
Purpose of the Study:
- To review and evaluate self-report questionnaires and biochemical markers for detecting alcohol problems in primary care.
- To provide guidance to general practitioners on effective alcohol screening methods.
- To recommend optimal strategies for routine alcohol screening in primary care.
Main Methods:
- Review of self-report screening tools including CAGE, MAST, SAAST, and AUDIT.
- Description and evaluation of biochemical markers such as liver enzymes (AST, ALT, GGT), MCV, and CDT.
- Discussion of combined use of self-reports and biochemical markers for improved validity.
- Exploration of selective and sequential screening approaches (e.g., AUDIT, TRAUMA questionnaire).
Main Results:
- Several self-report questionnaires and biochemical markers can aid in identifying problem drinkers.
- Combining screening methods can enhance the accuracy of alcohol problem detection.
- The AUDIT is recommended for routine screening in primary care.
- Selective or sequential screening strategies can address time constraints and patient concerns.
Conclusions:
- Alcohol screening using self-reports and biochemical markers should be a standard practice in primary care.
- The AUDIT is a valuable tool for routine alcohol problem screening.
- Tailored screening approaches can improve efficiency and effectiveness in primary care settings.
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