Nonspecific inhalative challenge tests--methods and importance

Nonspecific bronchial hyperresponsiveness is a common symptom, the prevalence depends especially on the inhalative exposure and on the status of atopy. Testing of nonspecific bronchial hyperresponsiveness is easy to perform and can be done with different methods. They all are reliable and safe for the patient. To assess the result of provocation challenge, it is necessary to look at all lung function parameters as well as on the clinical signs. A lot of persons with nonspecific bronchial hyperresponsiveness develop a constant airway disease within the next years. So, early detection of nonspecific bronchial hyperresponsiveness is very important to control these patients or for starting therapy.