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Propionibacterium acnes colonization in acne and nonacne
J J Leyden1, K J McGinley, B Vowels
1University of Pennsylvania Hospital, Philadelphia 19104, USA.
Abstract:
Propionibacterium acnes is a number of the resident bacterial flora and resides in sebaceous follicles. Age-related and body-dependent quantitative differences exist, indicating the role of sebum as an important ecological factor for P. acnes. Acne patients demonstrate marked increases in this organism which generates inflammation through a variety of mechanisms.