Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Systemic antibiotics for acne

J Meynadier1, M Alirezai

  • 1Service de Dermatologie, Hôpital Saint-Eloi, Montpellier, France.

Dermatology (Basel, Switzerland)
|April 29, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Origins of pain in HIV/AIDS.

Journal of back and musculoskeletal rehabilitation·2014
Same author

[Clinical and psychological correlation in acne: use of the ECLA and CADI scales].

Annales de dermatologie et de venereologie·2007
Same author

Results of a randomised, multicentre study comparing a new water-based gel of clindamycin 1% versus clindamycin 1% topical solution in the treatment of acne vulgaris.

European journal of dermatology : EJD·2005
Same author

[Narrow band UVB phototherapy in the treatment of widespread lichen planus].

Annales de dermatologie et de venereologie·2005
Same author

[Epithelial and melanotic skin tumors. Human papillomavirus (HPV) tumors].

Annales de dermatologie et de venereologie·2003
Same author

[Rosacea].

Annales de dermatologie et de venereologie·2003
Same journal

Survey on Difficult to Treat Tinea: A Sub-Saharan Africa Snapshot.

Dermatology (Basel, Switzerland)·2026
Same journal

Mpox Outbreaks Beyond Historically Endemic Regions: A Clinical Review of Vaccination Strategies and Public Health Challenges.

Dermatology (Basel, Switzerland)·2026
Same journal

Clinical Insights and Prognostic Factors in Frontal Fibrosing Alopecia and Lichen Planopilaris: A Retrospective Cohort Study.

Dermatology (Basel, Switzerland)·2026
Same journal

Descriptive Analysis of DRESS Reports from EudraVigilance and DRESS Cases from the RegiSCAR-project.

Dermatology (Basel, Switzerland)·2026
Same journal

The Role of the Vagus Nerve and Its Stimulation in Modulating Inflammatory Skin Diseases and Other Dermatologic Conditions: From Mechanisms to Therapeutics.

Dermatology (Basel, Switzerland)·2026
Same journal

Skin Barrier Dysfunction, Antimicrobial Peptide Alterations, and Microbiome Changes in Solid Cancer Patients Treated with Epidermal Growth Factor Receptor Inhibitors.

Dermatology (Basel, Switzerland)·2026
See all related articles

Systemic antibiotics effectively treat moderate to severe acne, though treatment failure necessitates alternatives like isotretinoin. Antibiotic mechanisms extend beyond antimicrobial action, influencing inflammation and bacterial lipase production.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Antibiotic therapy is a cornerstone in managing acne vulgaris.
  • Systemic antibiotics are prescribed for moderate-to-severe acne or when acne significantly impacts a patient's quality of life.

Purpose of the Study:

  • To review the efficacy, side effects, and mechanisms of action of systemic antibiotics used in acne treatment.
  • To provide guidance on antibiotic selection during pregnancy and lactation.

Main Methods:

  • Literature review of commonly used systemic antibiotics for acne.
  • Discussion of antibiotic efficacy, safety profiles, and proposed mechanisms of action.
  • Consideration of specific patient populations, including pregnant and nursing women.

Main Results:

Related Experiment Videos

  • Tetracyclines (doxycycline, minocycline), erythromycin, co-trimoxazole, and trimethoprim are effective systemic options.
  • Excellent results are frequently observed, but treatment failure may require alternative therapies like isotretinoin.
  • Erythromycin is the preferred antibiotic during pregnancy; tetracyclines are generally contraindicated but pose minimal risk in nursing mothers.

Conclusions:

  • Systemic antibiotics offer significant benefits for acne management.
  • Their therapeutic effects involve both antimicrobial activity and modulation of inflammatory pathways.
  • Careful consideration of side effects and patient-specific factors, such as pregnancy, is crucial for optimal treatment outcomes.