Third ventricular neuroepithelial cyst originating from the massa intermedia--case report

Area of Science:

• Neurology
• Neurosurgery
• Developmental Neurobiology

Background:

• Neuroepithelial cysts are rare developmental lesions.
• Cysts in the third ventricle can cause significant neurological symptoms.
• The massa intermedia is an uncommon origin for intracranial cysts.

Purpose of the Study:

• To report a case of a neuroepithelial cyst originating from the massa intermedia.
• To describe the clinical presentation, diagnostic imaging, surgical management, and histopathological findings.
• To discuss the potential embryological basis for this rare condition.

Main Methods:

• Case presentation of a 47-year-old female with progressive emotional disturbance.
• Diagnostic imaging including computed tomography (CT) and magnetic resonance imaging (MRI).
• Endoscopic surgical cyst removal and subsequent histopathological examination.

Main Results:

• Imaging revealed a third ventricular cyst causing hydrocephalus.
• Endoscopic surgery identified the cyst's origin at the massa intermedia.
• Histology confirmed the diagnosis of a neuroepithelial cyst.

Conclusions:

• Neuroepithelial cysts of the massa intermedia are rare but can cause significant neurological deficits.
• Endoscopic surgery is a viable treatment option.
• The cyst's origin may be related to the persistence of neuroepithelial crest remnants.