Analog vs. digital photogrammetry for optic cup analysis

This report compares the reproducibility of analog and digital photogrammetry for topographical analysis of the optic cup. Ten simultaneous stereophotographs of each of three optic discs were taken with the Zeiss fundus camera plus a twin-prism stereoseparator. Digital processing produced photogrammetric contours of the optic cup and estimates of its geometry. Optic cup contours from the same stereopairs were also drawn with an analog stereoplotter and were analyzed by manual planimetry. The reproducibility of digital photogrammetry and analysis for estimation of cup depth, cup width, cup cross sectional area, and cup volume was concluded to be generally superior to the reproducibility of analog photogrammetry and manual analysis.