Basal cell carcinoma of the periocular region
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Updated: Oct 30, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
J P Arlette1, A Carruthers, W J Threlfall
1Division of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.
Background:
Basal cell carcinomas of the periocular area present a particular challenge because of the likelihood of damage to vital structures.
Objective:
More than 10-years experience of treating basal cell carcinomas by Mohs micrographic surgery was reviewed.
Methods:
Chart analysis of 233 periocular basal cell carcinomas was performed. All patients were contacted either in clinical follow-up or by telephone review.
Results:
Two hundred and thirty-three periocular basal cell carcinomas were analyzed out of a total of 3, 192 basal cell carcinomas treated during this period (7.3%). Patients ranged in age from 17 to 102 years with a mean age of 58.8 years and a median of 59.0 years. Of the patients, 54.5% were female. Mohs micrographic surgery was the prime therapy in 177 patients (75. 9%). Of the lesions, 48.5% occurred in the medial canthal area, 35. 2% on the lower eyelid, 10.7% on the upper eyelid, and 5.6% on the lateral canthus. There was no significant difference between the left/right distribution in males and females. The average follow-up time was 34 months (standard deviation 26.38 months). A cumulative rate of no recurrence tabulated by modified life table analysis was 0.9864.
Conclusion:
This study further documents the problems associated with basal cell carcinoma of the periocular area as well as the value of Mohs micrographic surgery as treatment.
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