Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Desmoplastic fibroblastoma]

C Povýsil1

  • 1II. patologickoanatomický ústav 1. LF UK a Katedra patologické anatomie IPVZ, Praha.

Ceskoslovenska Patologie
|April 30, 1998
PubMed
Summary
This summary is machine-generated.

Two benign soft tissue tumors, desmoplastic fibroblastoma (collagenous fibroma), were analyzed. These foot tumors exhibit characteristic cellular and stromal features, aiding in their diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Monoclonal gammopathy of clinical signifi cance with osteosclerotic lesions - a case report and a literature review.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2024
Same author

Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features.

Folia biologica·2023
Same author

Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features.

Folia biologica·2023
Same author

New Developments in Understanding the Histological Structure of Human Ear Cartilage.

Folia biologica·2020
Same author

[Structural Damage to the Hamstring Graft due to Interaction with Fixation Material and its Effect on Biomechanical Properties of ACL Reconstruction].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2017
Same author

Iron Overload Causes Alterations of E-Cadherin in the Liver.

Folia biologica·2016
Same journal

EBV-associated plasmacytic variant of Castleman disease: more than a decade-long diagnostic odyssey - a case report.

Ceskoslovenska patologie·2026
Same journal

Castleman-Like Lymphadenopathy in a Patient with Mixed Connective Tissue Disease: A Case Report and Review of the Literature.

Ceskoslovenska patologie·2026
Same journal

Targeted gene expression profiling as a tool for diagnostic cell-of-origin determination and prognostic stratification in diffuse large B-cell lymphoma.

Ceskoslovenska patologie·2026
Same journal

The advantages and limitations of the new FIGO 2023 staging system for endometrial carcinoma from the perspective of the clinician and pathologist.

Ceskoslovenska patologie·2026
Same journal

Castleman disease - one name, many faces.

Ceskoslovenska patologie·2026
Same journal

Testing Claudin 18.2 Expression in Gastric and Gastroesophageal Junction Adenocarcinoma: Current Status and Near‑Future Outlook.

Ceskoslovenska patologie·2026
See all related articles

Area of Science:

  • Pathology
  • Soft Tissue Tumors
  • Histology

Context:

  • Desmoplastic fibroblastoma (collagenous fibroma) is a rare benign soft tissue neoplasm.
  • Accurate diagnosis is crucial for appropriate patient management.
  • Understanding the histological and immunohistochemical features aids in differential diagnosis.

Purpose:

  • To describe the light microscopic, ultrastructural, and immunohistochemical characteristics of two cases of desmoplastic fibroblastoma (collagenous fibroma).
  • To provide detailed diagnostic criteria for this specific benign soft tissue tumor.

Summary:

  • Two well-demarcated benign soft tissue tumors, identified as desmoplastic fibroblastoma (collagenous fibroma), were located in the foot.
  • Microscopic examination revealed stellate or spindle-shaped cells within a hypocellular fibrous or fibromyxoid stroma.

Related Experiment Videos

  • Immunohistochemistry showed diffuse vimentin positivity and focal positivity for smooth muscle actin and muscle-specific actin, consistent with fibroblast and myofibroblast differentiation.

    • Impact:

    • This detailed characterization aids pathologists in accurately diagnosing desmoplastic fibroblastoma (collagenous fibroma).
    • Improved diagnostic accuracy can lead to better clinical management and prognosis for patients with these benign tumors.