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Updated: Aug 12, 2026
07:34
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Characterization of marker chromosomes by fish using microdissected probes from old Carnoy-fixed cells: report of two
Y Chinen1, T Tohma, Y Izumikawa
1Department of Pediatrics, University of the Ryukyus School of Medicine, Okinawa, Japan.
The Japanese Journal of Human Genetics
|April 30, 1998
Abstract:
We reported on two patients with a de novo marker chromosome of which the origins were successfully identified by FISH using microdissected probes. These probes were established by microdissections of extra chromosomal segments from Carnoy-fixed cells stored at -20 degrees C for several years. Using these probes, we could verify partial 1q32 trisomy in a patient with 17p+ as well as partial 16q2 trisomy in another patient with 4p+.
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