Related Experiment Videos
Retinal sensitivity measurement over drusen using scanning laser ophthalmoscope microperimetry
Y Takamine1, K Shiraki, M Moriwaki
1Department of Ophthalmology, Osaka City University Medical School, Japan.
Summary
Large drusen, but not soft drusen, can significantly decrease retinal sensitivity. This study investigated retinal sensitivity over various drusen types using microperimetry, revealing potential functional impacts of large drusen.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Visual Function Testing
Background:
- Retinal sensitivity over drusen has been previously studied.
- Scanning laser ophthalmoscopy was used to examine retinal sensitivity.
Purpose of the Study:
- To examine retinal sensitivity over drusen.
- To confirm previous reports on retinal sensitivity over drusen.
Main Methods:
- Microperimetry was performed using a scanning laser ophthalmoscope.
- 23 eyes from 19 subjects (age 42-86) were examined.
- 54 large drusen (soft and other) were classified and analyzed.
Main Results:
- A statistically significant decrease in retinal sensitivity was observed over 15 of 29 large drusen (p < 0.02).
- The sensitivity decrease exceeded 5 dB compared to non-drusen areas.
- No significant sensitivity decrease was found over 25 soft drusen.
Conclusions:
- Large drusen can negatively influence retinal sensitivity.
- Retinal sensitivity and function may be impacted by large drusen.