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Updated: Oct 29, 2026

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
Published on: October 16, 2018
[Immunology in clinical practice. XII. Indications for T-Cell-mediated immunotherapy of cancer]
1Eli Lilly Nederland, Medische Afdeling, Leiden.
Abstract:
In a limited number of cases, T cell based cancer immunotherapy has proven its clinical efficacy. Indications are restricted to certain haematological malignancies, relapsed after allogeneic bone marrow transplantation, and tumours against which an autologous T cell response can be elicited or boosted, such as melanomas and renal carcinomas. T cell based immunotherapy of non-immunogenic tumors is possible using bispecific antibodies.
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