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Progressive pan-colonic fibrosis secondary to oral administration of pancreatic enzymes
R L Moss1, C A Musemeche, R M Feddersen
1Packard Children's Hospital, Stanford University School of Medicine, Division of Pediatric Surgery, Palo Alto, California 94304, USA.
Pediatric Surgery International
|May 1, 1998
Abstract:
Most patients with cystic fibrosis require oral administration of pancreatic enzymes to treat pancreatic insufficiency. Recent use of higher-strength enzyme preparations in large doses has been found to be associated with fibrotic strictures of the colon. We report a case of pancolonic fibrosis due to pancreatic enzyme use.