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Tonsillitis and chronic psoriasis

P Wardrop1, R Weller, J Marais

  • 1Department of Otolaryngology, Royal Infirmary, Edinburgh, UK.

Clinical Otolaryngology and Allied Sciences
|May 1, 1998
PubMed
Summary
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Recurrent sore throats linked to streptococcal infection may worsen severe psoriasis. A study found one-third of psoriasis patients reported throat infections that exacerbated their skin condition, unlike eczema controls.

Area of Science:

  • Dermatology
  • Immunology
  • Microbiology

Background:

  • The link between streptococcal tonsillitis and guttate psoriasis is known.
  • The association between streptococcal infection and chronic psoriasis is less understood.
  • Psoriasis is a chronic inflammatory skin condition with various forms.

Purpose of the Study:

  • To investigate the relationship between streptococcal infections and severe chronic psoriasis.
  • To compare the history of sore throats and skin worsening in psoriasis patients versus eczema controls.

Main Methods:

  • A case-control study involving 35 patients with severe psoriasis and 35 age-matched eczema controls.
  • Patients were surveyed about their history of significant sore throats (requiring medical attention).

Related Experiment Videos

  • Inquiry into whether sore throats resulted in worsening of their skin condition.

    • Main Results:

    • One-third (33%) of patients with severe psoriasis reported recurrent sore throats that worsened their skin condition.
    • Only one (3%) of the 35 eczema controls reported a similar experience.
    • This suggests a potential link between streptococcal infections and psoriasis exacerbation.

    Conclusions:

    • Recurrent streptococcal infections may trigger or worsen severe chronic psoriasis.
    • Findings support a potential role for streptococcal bacteria in the pathogenesis of psoriasis.
    • Further research into the streptococcal-psoriasis association is warranted.