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Myometrial tissue in uterine septa
T G Zreik1, R N Troiano, R A Ghoussoub
1Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06520-8063, USA.
Summary
Uterine septa, often found in women with septate uteri, frequently contain myometrial tissue. This finding was confirmed through magnetic resonance imaging and histologic evaluation of resected uterine septa.
Area of Science:
- Reproductive Medicine
- Gynecologic Imaging
- Pathology
Background:
- Septate uterus is a common congenital uterine anomaly.
- The composition of uterine septa, particularly the presence of myometrium, is not fully understood.
Purpose of the Study:
- To determine the frequency of myometrial tissue within uterine septa.
- To characterize the histological composition of uterine septa.
Main Methods:
- Retrospective review of 29 women with septate uteri diagnosed via magnetic resonance imaging (MRI).
- MRI utilized a 1.5 Tesla scanner with high-resolution imaging sequences.
- Histologic evaluation of four resected uterine septa was performed.
Main Results:
- Magnetic resonance imaging revealed myometrium in all 17 partial septa.
- Complete septa in 12 patients showed myometrium in the upper portion and fibrous tissue in the lower portion.
- Histology confirmed the presence of myometrial tissue in all four resected septa.
Conclusions:
- Uterine septa are commonly composed of myometrial tissue.
- Understanding septum composition is crucial for accurate diagnosis and treatment planning in women with uterine anomalies.