[Pharma-Clinics. The drug of the month. Adapalene (Differin gel)]

Adapalene is a new topical retinoid derived from naphthoic acid with a selective effect on the epidermis. It is indicated for treatment of acne vulgaris, alone or with other antiacneic topicals. It displays comedolytic and anti-inflammatory activities. The only frequent adverse event is a mild skin irritation during the first two weeks of treatment.