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Updated: Aug 16, 2026

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
Published on: March 3, 2014
Reversal of renal failure and paraplegia after thoracoabdominal aneurysm repair
M D Widmann1, A DeLucia, J Sharp
1Division of Cardiothoracic and Vascular Surgery, The University of Iowa Hospitals and Clinics, Iowa City 52242-1062, USA.
Abstract:
Repair of ruptured thoracoabdominal aortic aneurysms is complicated by high rates of perioperative paraplegia, renal insufficiency, and mortality. This report describes a patient with a ruptured thoracoabdominal aortic aneurysm in whom preoperative acute renal failure was reversed with hemodialysis, aortic replacement, and renal revascularization. Prompt cerebrospinal fluid drainage reversed delayed-onset postoperative paraplegia and led to immediate, complete neurologic recovery.
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