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Related Experiment Videos

Late-onset bleb leaks after glaucoma filtering surgery

D S Greenfield1, J M Liebmann, J Jee

  • 1Department of Ophthalmology, The New York Eye and Ear Infirmary, NY 10003, USA.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|May 2, 1998
PubMed
Summary
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Late-onset focal bleb leaks are more common after glaucoma surgery using mitomycin C. Combined cataract and glaucoma surgery rarely results in late bleb leaks.

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Surgical Complications

Background:

  • Glaucoma filtering surgery aims to reduce intraocular pressure.
  • Conjunctival blebs are a common outcome of glaucoma surgery.
  • Late-onset bleb leaks can lead to serious complications.

Purpose of the Study:

  • To investigate the incidence of focal, late-onset conjunctival bleb leaks.
  • To identify risk factors associated with bleb leaks after glaucoma surgery.

Main Methods:

  • Prospective, cross-sectional analysis of 525 patients undergoing glaucoma filtering surgery.
  • Bleb characteristics (height, area, wall thickness) were assessed.
  • Focal leakage was detected using Seidel testing with slit-lamp biomicroscopy.

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Main Results:

  • Late-onset bleb leaks occurred in 3.7% of eyes treated with mitomycin C, compared to 1.4% with 5-fluorouracil.
  • Mitomycin C treatment was associated with thinner blebs.
  • Late leakage was infrequent after combined cataract and glaucoma surgery.

Conclusions:

  • Trabeculectomy with mitomycin C increases the risk of late-onset focal bleb leakage.
  • Late bleb leakage after combined cataract and glaucoma surgery is rare.