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Related Experiment Videos

Two hundred one consecutive living-donor nephrectomies

D Shaffer1, A I Sahyoun, P N Madras

  • 1Division of Organ Transplantation, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass 02215, USA.

Archives of Surgery (Chicago, Ill. : 1960)
|May 23, 1998
PubMed
Summary
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Living-donor nephrectomy for kidney transplantation has low morbidity and improving trends. Recent advancements include shorter hospital stays, advanced imaging, and increased use of unrelated donors, benefiting recipient outcomes.

Area of Science:

  • Nephrology
  • Transplant Surgery
  • Urology

Background:

  • Living-donor kidney transplantation is a critical treatment for end-stage renal disease.
  • Donor nephrectomy is a major surgical procedure with potential risks.
  • Understanding donor morbidity and recipient outcomes is essential for optimizing the procedure.

Purpose of the Study:

  • To evaluate donor morbidity and recipient outcomes in living-donor kidney transplantation.
  • To identify trends in donor nephrectomy over a decade.
  • To assess the safety and efficacy of living-donor kidney transplantation.

Main Methods:

  • Retrospective review of 201 living-donor kidney transplantations from January 1988 to June 1997.
  • Analysis of donor surgical complications, hospital stay, and preoperative imaging accuracy.

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  • Evaluation of recipient delayed graft function and patient/graft survival rates.

    • Main Results:

    • Major donor complications were rare (bleeding, pneumothorax, wound infection, pneumonia).
    • Mean donor hospital stay decreased significantly from 6.2 to 4.0 days.
    • Recipient survival rates were high (97% at 1 year, 90% at 5 years), with no difference between related and unrelated donors.

    Conclusions:

    • Living-donor nephrectomy is associated with low surgical morbidity.
    • Trends indicate shorter hospital stays, advanced imaging use (CT angiography), and increased unrelated donor utilization.
    • Living-donor kidney transplantation remains a safe and effective option with excellent long-term outcomes.