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Stent revascularization for atherosclerotic renal artery stenosis. 1-year clinical follow-up
G Dorros1, M R Jaff, L Mathiak
1William Dorrosisadore Feuer Interventional Cardiovascular Disease Foundation Ltd., Milwaukee, Wisconsin, USA.
Insights
Renal artery stent revascularization significantly lowered blood pressure in hypertensive patients. The procedure also maintained or improved kidney function for most patients after one year.
Area of Science:
- Cardiology
- Nephrology
- Vascular Surgery
Background:
- Renal artery stenosis (RAS) is a significant cause of secondary hypertension.
- Stent revascularization is a common treatment for RAS, but its long-term effects on blood pressure and renal function require ongoing evaluation.
Purpose of the Study:
- To assess the impact of renal artery stent revascularization on blood pressure control and renal function in patients with poorly controlled hypertension.
Main Methods:
- A cohort of patients with renal artery stenosis who underwent stent revascularization was monitored.
- Blood pressure (systolic and diastolic) and serum creatinine levels were measured at baseline and at 1-year follow-up.
Main Results:
- Systolic blood pressure decreased from 166 +/- 26 to 156 +/- 25 mmHg (P < 0.05).
- Diastolic blood pressure decreased from 86 +/- 14 to 80 +/- 13 mmHg (P < 0.05).
- Approximately two-thirds of patients experienced a decrease or stable creatinine levels at 1-year follow-up.
Conclusions:
- Renal artery stent revascularization demonstrates a beneficial effect on blood pressure control in patients with RAS.
- The procedure has a non-deleterious effect on renal function in the majority of treated patients.
Abstract:
Patients who had undergone stent revascularization of renal artery stenosis for poorly controlled hypertension, preservation of renal function, or both were monitored to assess the procedure's effect upon subsequent renal function and blood pressure control. At 1-year follow-up, systolic and diastolic blood pressures had significantly decreased (166 +/- 26 to 156 +/- 25 mmHg and 86 +/- 14 to 80 +/- 13 mmHg, respectively; P < 0.05), and creatinine levels decreased or remained stable in approximately two thirds of the patients. Renal artery stent revascularization appears to have a beneficial effect upon blood pressure control and a nondeleterious effect upon renal function in the majority of patients.