Related Experiment Videos
Compositional constraints in the extremely GC-poor genome of Plasmodium falciparum
H Musto1, S Cacciò, H Rodríguez-Maseda
1Sección Bioquímica, Facultad de Ciencias, Montevideo, Uruguay. hmusto@genetica.edu.uy
Memorias Do Instituto Oswaldo Cruz
|May 5, 1998
Abstract:
We have analyzed the compositional properties of coding (protein encoding) and non-coding sequences of Plasmodium falciparum, a unicellular parasite characterized by an extremely AT-rich genome. GC% levels, base and dinucleotide frequencies were studied. We found that among the various factors that contribute to the properties of the sequences analyzed, the most relevant are the compositional constraints which operate on the whole genome.