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Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach
E M Rabelo1, G R Franco, V A Azevedo
1Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
Memorias Do Instituto Oswaldo Cruz
|May 5, 1998
Abstract:
Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been described in S. mansoni. Among the newly discovered genes there are several of significant biological interest such as synaptophysin, NIFs-like and rho-GDP dissociation inhibitor.