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Cerebral vasculitis during FK 506 treatment in a liver transplant patient
G P Pizzolato1, R Sztajzel, K Burkhardt
1Division of Clinical Pathology, Geneva University Hospital, Switzerland.
Neurology
|May 5, 1998
Abstract:
The immunosuppressive agent FK 506 is widely used in liver transplant patients. Neurotoxicity is a major complication of its use. We report progressive and irreversible neurologic complications occurring in a 39-year-old woman who underwent liver transplantation and was treated with FK 506. Neuropathologic examination revealed multiple vasculitic lesions. The possibility of an FK 506-mediated toxic effect on the cerebral vessels is suggested.