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Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
Published on: March 24, 2017
[Analysis of B-epitopes formed on proteins after treatment with glutaraldehyde]
E M Kavun1, D V Kolibo, E G Borisova
1Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine.
Prikladnaia Biokhimiia I Mikrobiologiia
|May 6, 1998
Abstract:
Structural analysis of the B-epitopes formed on protein macromolecules by glutaraldehyde treatment with subsequent block of free active groups by glycine was performed. Two types of antigenic determinants recognized by different antibody populations were found by protein chemistry and immunochemistry techniques. An efficient method of blocking the antibodies to the epitopes formed on proteins by glutaraldehyde was developed.
