Human immunodeficiency virus (HIV) in America, 1981 to 1997: epidemiologic and therapeutic considerations

In the last 16 years, acquired immunodeficiency syndrome (AIDS) has evolved from a mysterious syndrome apparently afflicting only gay men, into a viral illness affecting every segment of society. Until the advent of combination antiretroviral therapy, HIV appeared to be universally fatal. New therapies and technologies have been developed offering normal or near-normal life spans for some people living with HIV. Coincident with the development of life-prolonging therapies has been the realization that competent HIV care requires the integration of medical care, social services, and psychological support services to promote therapeutic adherence and maximize quality of life.