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[Respiratory circuits and infections of the airway]
M Verri1, M Capuzzo, M R Rossi
1Istituto di Anestesiologia e Rianimazione, Università degli Studi, Ferrara.
Objective:
To study the effects of ventilator circuit changes on the rate of airway infections and to investigate the relationship between the microorganisms responsible for circuit colonization and those responsible for infection.
Design:
Prospective study, carried out in two different periods, of one year duration each.
Setting:
General Intensive Care Units (ICUs) in a University Hospital.
Patients:
Seventy-eight patients, requiring mechanical ventilation (VAM) for more than 5 days, were enrolled. They were divided into two groups: in the first (group I, n. 36, 1st period) the ventilator circuit was changed every 5 days; in the second (group II, n. 42, 2nd period) every 10 days.
Intervention:
Ventilator circuit change every 5 or 10 days. Daily culvert and filling of cascade humidifiers with sterile irrigation water. Daily replacement of mount catheter.
Measurements:
Qualitative cultures of tracheobronchial aspirate and of fluid from the humidifying cascades and the expiratory tubing traps.
Results:
The two groups were similar. Pneumonia and tracheobronchitis were found in the 25% and 11% of patients of group I and in 26% and 12% of those of group II respectively. The VAM duration was 26.5 +/- 15 days in patients who developed airway infection, and 12.9 +/- 11.6 days (p < 0.001) in patients who did not. The Gram+ organisms were predominant. An identical microorganism was found both in the tracheo-bronchial aspirate and in the circuit in 44 of 78 (56%) patients; no difference was found between infected (16 of 29) and non infected (28 of 49) patients.
Conclusions:
Changing the ventilator circuit every 10 days rather than every 5 days, does not increase the incidence of airway infections and result in considerable savings in the expenses of tubing and personnel time. The infection or colonization rates due to the same microorganisms are quite low and it seems not useful to make routine cultures of fluid from humidifying cascades and the expiratory tubing traps in order to characterize in time the microorganism that could be responsible of airway infections.
Insights
Changing ventilator circuits every 10 days instead of every 5 days does not increase airway infections in mechanically ventilated patients. This extended interval offers significant cost savings without compromising patient safety.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Hospital Infection Control
Background:
- Ventilator-associated airway infections are a significant concern in intensive care units.
- Current protocols often involve frequent ventilator circuit changes, incurring substantial costs and resource utilization.
Purpose of the Study:
- To evaluate the impact of ventilator circuit change frequency (5 vs. 10 days) on airway infection rates.
- To determine the correlation between microbial colonization of ventilator circuits and subsequent patient infections.
Main Methods:
- A prospective study comparing two groups of mechanically ventilated patients (n=78) over two one-year periods.
- Group I: ventilator circuit changed every 5 days; Group II: changed every 10 days.
- Cultures of respiratory secretions and ventilator components were analyzed.
Main Results:
- No significant difference in pneumonia or tracheobronchitis rates between the 5-day and 10-day circuit change groups.
- Identical microorganisms were found in patient aspirates and circuits in 56% of cases, with no difference between infected and non-infected patients.
- Patients who developed infections had significantly longer durations of mechanical ventilation.
Conclusions:
- Extending ventilator circuit changes to every 10 days is safe and does not increase airway infection incidence.
- This practice leads to considerable cost savings in materials and personnel time.
- Routine cultures of ventilator components are not recommended for predicting or managing airway infections.
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