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Related Experiment Videos

[Inflammatory bowel disease and pregnancy]

N Hovdenak1, E Schlichting

  • 1Medisinsk avdeling, Diakonissehjemmets Sykehus Haraldsplass, Bergen.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|May 6, 1998
PubMed
Summary

Pregnancy typically does not significantly alter inflammatory bowel disease (IBD) course. Most IBD medications are safe during pregnancy, and planned pregnancies in remission are recommended for women with ulcerative colitis or Crohn's disease.

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Area of Science:

  • Gastroenterology and Immunology
  • Reproductive Health

Context:

  • Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, frequently affects individuals during their reproductive years.
  • Managing IBD during pregnancy presents challenges due to potential medication side effects and patient concerns.

Purpose:

  • To review the impact of pregnancy on the course of inflammatory bowel disease.
  • To provide guidance on managing IBD during pregnancy, including treatment and surgical interventions.
  • To assess the safety of common IBD medications during pregnancy.

Summary:

  • Pregnancy generally has a minimal effect on the natural course of ulcerative colitis and Crohn's disease.
  • The relapse rate in IBD patients is only slightly elevated if the disease is active at conception.

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  • Standard treatments, including sulfasalazine, 5-ASA, and steroids, are generally safe during pregnancy; planned pregnancies during disease remission are advised.

    • Impact:

    • This information aids clinicians in counseling IBD patients considering pregnancy.
    • It supports the continuation of essential IBD therapies throughout gestation.
    • Highlights the safety of most IBD medications, reducing patient anxiety and improving outcomes.