Related Experiment Videos
Effects of age and respiration on right ventricular diastolic filling patterns in normal children
1Department of Pediatrics, Gezhouba Central Hospital, Yichang, People's Republic of China.
Insights
Right ventricular diastolic filling in children varies with age and respiration. Doppler echocardiography shows peak flow velocities are higher during inspiration, impacting filling times and integrals.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Cardiovascular Physiology
Background:
- Right ventricular diastolic function is crucial for overall cardiac health.
- Doppler echocardiography is a key tool for assessing diastolic function.
- Understanding normal variations in pediatric diastolic filling is essential.
Purpose of the Study:
- To assess right ventricular diastolic filling in normal Chinese children.
- To investigate the influence of age and respiration on diastolic filling parameters.
- To provide recommendations for standardized echocardiographic measurements.
Main Methods:
- Doppler echocardiography was used to interrogate diastolic transtricuspid valve flow.
- 88 normal Chinese children were included in the study.
- Transtricuspid flow parameters were analyzed in relation to age and respiratory phase.
Main Results:
- Age-dependent differences were observed in filling times, correlating with heart rate changes.
- Peak transtricuspid flow velocities, filling times, and velocity-time integrals were significantly higher during inspiration compared to expiration.
- Respiration markedly influenced right ventricular diastolic filling parameters.
Conclusions:
- Age and respiration significantly affect right ventricular diastolic filling parameters in children.
- Standardization of measurements for respiratory phase is recommended.
- Right ventricular diastolic function assessment should consider end-inspiration and end-expiration measurements.
Abstract:
Right ventricular diastolic filling was assessed in 88 normal Chinese children using Doppler echocardiographic interrogation of diastolic transtricuspid valve flow. Any influences of age and respiration on right ventricular diastolic filling were also investigated. The results showed that age-dependent differences were apparent for filling times, associated with the decrease in heart rate with increasing age. In addition, peak transtricuspid flow velocities were markedly greater in inspiration than in expiration, with corresponding increases in filling times and velocity-time integrals. The influence of age and respiration on transtricuspid flow parameters should be considered in the evaluation of right ventricular diastolic function by Doppler echocardiography. We believe that measurements should be standardized for respiratory phase and that right ventricular diastolic function parameters should be taken at end-inspiration and end-expiration, respectively.