Estimates of radiation dose to the embryo from nuclear medicine procedures

These phantom studies and computer calculations provide a direct means of estimating the radiation dose to the embryo resulting from the administration of a radiopharmaceutical to the mother during organogenesis. The specific absorbed fractions to the embryo from 19 source organs were computed for 12 monoenergetic photon energies. Tables of absorbed dose per unit cumulated activity, S, for the embryo as a target organ have been assembled for 99mTc, 111In, 113mIn, 123I, 131I, and 133Xe. In addition, the dose to the embryo was calculated for several of the radiopharmaceuticals for which the MIRD Committee has published dose estimate reports.