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Familial dermatomyositis

A Andrews¹, P Hickling, C Hutton

¹Rheumatology Department, Mount Gould Hospital, Plymouth.

British Journal of Rheumatology

|May 6, 1998

Summary

This summary is machine-generated.

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Familial dermatomyositis (DM) is rare, especially in young children. This case highlights a mother and daughter with DM, with the child requiring a combination therapy of methotrexate and prednisolone for effective management.

Area of Science:

Rheumatology
Pediatrics
Genetics

Background:

Familial dermatomyositis (DM) is an uncommon autoimmune condition.
Previous reports of pediatric DM have not included cases in children under four years old.

Observation:

A 27-year-old mother and her 2-year-old daughter were diagnosed with dermatomyositis.
The mother responded well to corticosteroid treatment.
The daughter showed resistance to corticosteroids.

Findings:

The child with dermatomyositis was successfully treated with a combination of methotrexate and prednisolone.
Another daughter exhibited only the skin manifestations of DM without muscle involvement.

Implications:

Related Experiment Videos

This case expands the understanding of familial dermatomyositis in pediatric populations.

It suggests that combination therapy may be effective for steroid-resistant pediatric DM.

Highlights the variable presentation of DM within a single family.