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Granulomatous hepatitis in pasteurella multocida infection
1Service de Radiologie A, Hôpital Pellegrin, Place A Raba Léon, F-33076, Bordeaux Cedex, France.
Abstract:
Numerous diseases can lead to multilocular lesions of the liver. The authors report a rare pediatric case of hepatic granulomas due to Pasteurella multocida: a 7-year-old girl with chronic fever was investigated by sonography and CT scan, demonstrating mesenteric lymph node enlargement and numerous small hepatic lesions. After surgical biopsy, histopathology of the liver specimens showed pyogenic granuloma, with serologic testing positive for Pasteurella multocida. Treatment with a tetracycline and corticosteroids was successful. Pasteurella multocida infection, despite its habitual benign course, should be suspected among differential diagnoses of lymphogranulomatous affections with hepatic involvement. No case of liver and lymph node foci in a child has been previously described.
Insights
A rare pediatric case reveals hepatic granulomas caused by Pasteurella multocida infection. This finding is crucial for diagnosing pediatric liver and lymph node lesions.
Area of Science:
- Pediatric Infectious Diseases
- Hepatology
- Microbiology
Background:
- Multilocular liver lesions can stem from various diseases.
- Pasteurella multocida is a bacterium typically causing benign infections.
Observation:
- A 7-year-old girl presented with chronic fever, mesenteric lymphadenopathy, and numerous hepatic lesions.
- Imaging revealed small liver lesions and enlarged lymph nodes.
Findings:
- Histopathology confirmed pyogenic granulomas in the liver.
- Serologic tests identified Pasteurella multocida as the causative agent.
- This is the first reported case of hepatic and lymph node Pasteurella multocida foci in a child.
Implications:
- Pasteurella multocida should be considered in the differential diagnosis of pediatric lymphogranulomatous diseases with hepatic involvement.
- Early diagnosis and treatment with antibiotics like tetracycline and corticosteroids can be effective.