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Updated: Aug 2, 2026
Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
Changes in body fat: measurements by neutron activation, densitometry and dual energy X-ray absorptiometry
S J Ryde1, R Eston, M A Laskey
1Department of Medical Physics and Clinical Engineering, Singleton Hospital, Swansea, U.K.
Abstract:
The measurement of body fat in ten subjects (BMI from 22 to 43 kg/m2), and in particular the changes arising from a ketogenic diet, by the techniques of in vivo neutron activation analysis (NAA), densitometry (using two- and four-compartment models) by under water weighing (UWW) and dual energy X-ray absorptiometry (DXA) was compared. The association between techniques for the fat changes was generally high (r = 0.70 to 0.98) and significant (p < 0.05). Assessment of agreement between DXA and the other techniques revealed discrepancies with significant slope and high association (r = -0.81 and -0.64). Whilst NAA and UWW appeared to measure similar changes, DXA underestimated small changes.
